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Inform postmenopausal women of possible less serious but common adverse reactions of estrogenalone therapy such as headachebreast pain and tendernessnausea and vomiting.
Breakthrough bleeding and spotting may occur during the first months of treatmentIf break-through bleeding or spotting appears after some time on therapyor continues after treatment has been discontinuedthe reason should be investigatedwhich may include endometrial biopsy to exclude endometrial malignancy.
This medication may rarely cause serious problems from blood clotssuch as heart attacksstrokesdeep vein thrombosispulmonary embolismGet medical help right away if you have any serious side effectsincludingchest/jaw/left arm painunusual sweatingsudden/severe headacheweakness on one side of the bodyconfusionslurred speechsudden vision changessuch as partial/complete blindnesspain/redness/swelling of legstingling/weakness/numbness in the arms/legstrouble breathingcoughing up bloodsudden dizziness/fainting.
Inform postmenopausal women of possible serious adverse reactions of estrogen-alone therapy including Cardiovascular DisordersMalignant Neoplasmsand Probable Dementiasee WARNINGS AND PRECAUTIONS
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because conjugated estrogens like premarin can pass into breast milk and harm a nursing baby you should not breast-feed while taking premarin.